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Angiotensin II stimulates fibronectin protein synthesis via a Gβγ/arachidonic acid-dependent pathway
In rabbit proximal tubular cells, ANG II type 2-receptor (AT(2))-induced arachidonic acid release is PLA(2) coupled and dependent of G protein βγ (Gβγ) subunits. Moreover, ANG II activates ERK1/2 and transactivates EGFR via a c-Src-dependent mechanism. Arachidonic acid has been shown to mimic this e...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121571/ https://ncbi.nlm.nih.gov/pubmed/24920755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00094.2014 |
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