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Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1.

The cyclic enzymatic function of a cytochrome P450, as it catalyzes the oxygen-dependent metabolism of many organic chemicals, requires the delivery of two electrons to the hemeprotein. In general these electrons are transferred from NADPH to the P450 via an FMN- and FAD-containing flavoprotein (NAD...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Faulkner, K M, Shet, M S, Fisher, C W, Estabrook, R W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41214/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7705
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