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High-Content Screening in Zebrafish Embryos Identifies Butafenacil as a Potent Inducer of Anemia

Using transgenic zebrafish (fli1:egfp) that stably express enhanced green fluorescent protein (eGFP) within vascular endothelial cells, we recently developed and optimized a 384-well high-content screening (HCS) assay that enables us to screen and identify chemicals affecting cardiovascular developm...

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Détails bibliographiques
Auteurs principaux: Leet, Jessica K., Lindberg, Casey D., Bassett, Luke A., Isales, Gregory M., Yozzo, Krystle L., Raftery, Tara D., Volz, David C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121296/
https://ncbi.nlm.nih.gov/pubmed/25090246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104190
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