Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS

Gentamicin, an aminoglycoside antibiotic, is used for the treatment of serious Gram-negative infections. However, its usefulness is limited by its nephrotoxicity. Sildenafil, a selective phosphodiesterase-5 inhibitor, was reported to prevent or decrease tissue injury. The aim of this study is to eva...

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Autores principales: Morsy, Mohamed A., Ibrahim, Salwa A., Amin, Entesar F., Kamel, Maha Y., Rifaai, Rehab A., Hassan, Magdy K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121185/
https://ncbi.nlm.nih.gov/pubmed/25120567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/489382
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