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A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease

Alzheimer's disease (AD), the leading cause of dementia in the aging population, is characterized by the presence of neuritic plaques, neurofibrillary tangles and extensive neuronal apoptosis. Neuritic plaques are mainly composed of aggregates of amyloid-β (Aβ) protein while neurofibrillary tan...

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Detalhes bibliográficos
Main Authors: Modi, Khushbu K., Jana, Arundhati, Ghosh, Supurna, Watson, Richard, Pahan, Kalipada
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121132/
https://ncbi.nlm.nih.gov/pubmed/25089827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103606
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