Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons

Non-invasive early detection methods have the potential to reduce mortality rates of both cancer and infectious diseases. Here, we present a novel assay by which tethered cationic lipoplex nanoparticles containing molecular beacons (MBs) can capture cancer cell-derived exosomes or viruses, and ident...

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Autori principali: Wu, Yun, Kwak, Kwang Joo, Agarwal, Kitty, Marras, Alexander, Wang, Chao, Mao, Yicheng, Huang, Xiaomeng, Ma, Junyu, Yu, Bo, Lee, Robert, Vachani, Anil, Marcucci, Guido, Byrd, John C., Muthusamy, Natarajan, Otterson, Gregory, Huang, Kun, Castro, Carlos E., Paulaitis, Michael, Nana-Sinkam, Serge P., Lee, L. James
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121114/
https://ncbi.nlm.nih.gov/pubmed/24102152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac401983w
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