Icariin Ameliorates Cigarette Smoke Induced Inflammatory Responses via Suppression of NF-κB and Modulation of GR In Vivo and In Vitro

PURPOSE: To investigate the effects of icariin, a major constituent of flavonoids isolated from the herb Epimedium, on cigarette smoke (CS) induced inflammatory responses in vivo and in vitro. METHODS: In vivo, BALB/c mice were exposed to smoke of 15 cigarettes for 1 h/day, 6 days/week for 3 months...

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Detalhes bibliográficos
Main Authors: Li, Lulu, Sun, Jing, Xu, Changqing, Zhang, Hongying, Wu, Jinfeng, Liu, Baojun, Dong, Jingcheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121073/
https://ncbi.nlm.nih.gov/pubmed/25089961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102345
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