Netrin-1 Induces MMP-12-Dependent E-Cadherin Degradation Via the Distinct Activation of PKCα and FAK/Fyn in Promoting Mesenchymal Stem Cell Motility

Netrin-1 (Ntn-1) is a potent inducer of neuronal cell migration; however, its molecular mechanism that guides the migratory behavior of stem cells has not been characterized. In this study, we investigate the role of Ntn-1 in promoting the motility of human umbilical cord blood-derived mesenchymal s...

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Bibliographic Details
Main Authors: Lee, Sei-Jung, Jung, Young Hyun, Oh, Sang Yub, Yong, Min Sik, Ryu, Jung Min, Han, Ho Jae
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Original Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121046/
https://ncbi.nlm.nih.gov/pubmed/24738865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0632
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