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Addicted to MYCN? A new connection to yet another pediatric tumor
Recurrent mutations in H3F3A at K27 and G34 are frequent in pediatric GBM, but it is unclear how these mutations promote tumorigenesis. In this issue of Cancer Discovery, Jones and colleagues demonstrate that mutation at G34 in H3F3A result in elevated expression of MYCN as a potential mechanism in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120990/ https://ncbi.nlm.nih.gov/pubmed/23658294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0126 |
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