Human XCR1(+) Dendritic Cells Derived In Vitro from CD34(+) Progenitors Closely Resemble Blood Dendritic Cells, Including Their Adjuvant Responsiveness, Contrary to Monocyte-Derived Dendritic Cells

Human monocyte-derived dendritic cell (MoDC) have been used in the clinic with moderately encouraging results. Mouse XCR1(+) DC excel at cross-presentation, can be targeted in vivo to induce protective immunity, and share characteristics with XCR1(+) human DC. Assessment of the immunoactivation pote...

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Hauptverfasser: Balan, Sreekumar, Ollion, Vincent, Colletti, Nicholas, Chelbi, Rabie, Montanana-Sanchis, Frédéric, Liu, Hong, Vu Manh, Thien-Phong, Sanchez, Cindy, Savoret, Juliette, Perrot, Ivan, Doffin, Anne-Claire, Fossum, Even, Bechlian, Didier, Chabannon, Christian, Bogen, Bjarne, Asselin-Paturel, Carine, Shaw, Michael, Soos, Timothy, Caux, Christophe, Valladeau-Guilemond, Jenny, Dalod, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2014
Schlagworte:
Clinical and Human Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120898/
https://ncbi.nlm.nih.gov/pubmed/25009205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401243
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