NF-κB in The Mechanism of Brain Edema in Acute Liver Failure: Studies in Transgenic Mice

Astrocyte swelling and brain edema are major complications of the acute form of hepatic encephalopathy (acute liver failure, ALF). While elevated brain ammonia level is a well-known etiological factor in ALF, the mechanism by which ammonia brings about astrocyte swelling is not well understood. We r...

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Bibliographic Details
Main Authors: Jayakumar, A.R., Bethea, J.R., Tong, X.Y., Gomez, J., Norenberg, M.D.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120888/
https://ncbi.nlm.nih.gov/pubmed/21087666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.10.021
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