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Expanding the View of Proton Pumping in Cytochrome c Oxidase through Computer Simulation
In cytochrome c oxidase (CcO), a redox-driven proton pump, protons are transported by the Grotthuss shuttling via hydrogen-bonded water molecules and protonatable residues. Proton transport through the D-pathway is a complicated process that is highly sensitive to alterations in the amino acids or t...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120846/ https://ncbi.nlm.nih.gov/pubmed/22178790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2011.11.017 |
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