Loss of Methyl-CpG–Binding Domain Protein 2 Enhances Endothelial Angiogenesis and Protects Mice Against Hind-Limb Ischemic Injury

BACKGROUND: Despite intensive investigation, how DNA methylation influences endothelial function remains poorly understood. We used methyl-CpG–binding domain protein 2 (MBD2), an interpreter for DNA methylome–encoded information, to dissect the impact of DNA methylation on endothelial function in bo...

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Autores principales: Rao, Xiaoquan, Zhong, Jixin, Zhang, Shu, Zhang, Yushan, Yu, Qilin, Yang, Ping, Wang, Mong-Heng, Fulton, David J., Shi, Huidong, Dong, Zheng, Wang, Daowen, Wang, Cong-Yi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120778/
https://ncbi.nlm.nih.gov/pubmed/21670230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.966408
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