Serotonin 2c receptor RNA editing in major depression and suicide

OBJECTIVES: mRNA for serotonin 2C receptor (5-HT(2C)R) undergoes editing which results in numerous isoforms. More highly edited isoforms exhibit decreased function. We recently found greater 5-HT(2C)R editing in suicide victims with prior bipolar disorder (BPD) or schizophrenia (SZ) compared with no...

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Main Authors: Lyddon, Rebecca, Dwork, Andrew J., Keddache, Mehdi, Siever, Larry J., Dracheva, Stella
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120662/
https://ncbi.nlm.nih.gov/pubmed/22404657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15622975.2011.630406
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