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The role of cysteine proteases in hypoxia-induced rat renal proximal tubular injury.

The role of the lysosomal proteases cathepsins B and L and the calcium-dependent cytosolic protease calpain in hypoxia-induced renal proximal tubular injury was investigated. As compared to normoxic tubules, cathepsin B and L activity, evaluated by the specific fluorescent substrate benzyloxycarbony...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Edelstein, C L, Wieder, E D, Yaqoob, M M, Gengaro, P E, Burke, T J, Nemenoff, R A, Schrier, R W
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7662
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