Secretion of Prohormone of B-Type Natriutretic Peptide, proBNP1–108, is Increased in Heart Failure

OBJECTIVES: Using a novel, specific assay for proBNP(1–108) we tested the hypotheses that proBNP(1–108) is secreted by both non-failing and failing human hearts and that proBNP(1–108) secretion is increased in failing hearts. BACKGROUND: The prohormone of B-type natriuretic peptide (proBNP(1–108)) i...

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Main Authors: Costello-Boerrigter, Lisa C., Lapp, Harald, Boerrigter, Guido, Lerman, Amir, Bufe, Alexander, Macheret, Fima, Heublein, Denise M., Larue, Catherine, Burnett, John C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120112/
https://ncbi.nlm.nih.gov/pubmed/24621871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchf.2013.03.001
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