Efficient de novo assembly of highly heterozygous genomes from whole-genome shotgun short reads

Although many de novo genome assembly projects have recently been conducted using high-throughput sequencers, assembling highly heterozygous diploid genomes is a substantial challenge due to the increased complexity of the de Bruijn graph structure predominantly used. To address the increasing deman...

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Detalhes bibliográficos
Main Authors: Kajitani, Rei, Toshimoto, Kouta, Noguchi, Hideki, Toyoda, Atsushi, Ogura, Yoshitoshi, Okuno, Miki, Yabana, Mitsuru, Harada, Masayuki, Nagayasu, Eiji, Maruyama, Haruhiko, Kohara, Yuji, Fujiyama, Asao, Hayashi, Tetsuya, Itoh, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120091/
https://ncbi.nlm.nih.gov/pubmed/24755901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.170720.113
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