Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Endogenous retroelements (EREs) account for about half of the mouse or human genome, and their potential as insertional mutagens and transcriptional perturbators is suppressed by early embryonic epigenetic silencing. Here, we asked how ERE control is maintained during the generation of induced pluri...

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Main Authors: Friedli, Marc, Turelli, Priscilla, Kapopoulou, Adamandia, Rauwel, Benjamin, Castro-Díaz, Nathaly, Rowe, Helen M., Ecco, Gabriela, Unzu, Carmen, Planet, Evarist, Lombardo, Angelo, Mangeat, Bastien, Wildhaber, Barbara E., Naldini, Luigi, Trono, Didier
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120079/
https://ncbi.nlm.nih.gov/pubmed/24879558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.172809.114
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