Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Endogenous retroelements (EREs) account for about half of the mouse or human genome, and their potential as insertional mutagens and transcriptional perturbators is suppressed by early embryonic epigenetic silencing. Here, we asked how ERE control is maintained during the generation of induced pluri...

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Detalhes bibliográficos
Main Authors: Friedli, Marc, Turelli, Priscilla, Kapopoulou, Adamandia, Rauwel, Benjamin, Castro-Díaz, Nathaly, Rowe, Helen M., Ecco, Gabriela, Unzu, Carmen, Planet, Evarist, Lombardo, Angelo, Mangeat, Bastien, Wildhaber, Barbara E., Naldini, Luigi, Trono, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120079/
https://ncbi.nlm.nih.gov/pubmed/24879558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.172809.114
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