Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Endogenous retroelements (EREs) account for about half of the mouse or human genome, and their potential as insertional mutagens and transcriptional perturbators is suppressed by early embryonic epigenetic silencing. Here, we asked how ERE control is maintained during the generation of induced pluri...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Friedli, Marc, Turelli, Priscilla, Kapopoulou, Adamandia, Rauwel, Benjamin, Castro-Díaz, Nathaly, Rowe, Helen M., Ecco, Gabriela, Unzu, Carmen, Planet, Evarist, Lombardo, Angelo, Mangeat, Bastien, Wildhaber, Barbara E., Naldini, Luigi, Trono, Didier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2014
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120079/
https://ncbi.nlm.nih.gov/pubmed/24879558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.172809.114
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