Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Endogenous retroelements (EREs) account for about half of the mouse or human genome, and their potential as insertional mutagens and transcriptional perturbators is suppressed by early embryonic epigenetic silencing. Here, we asked how ERE control is maintained during the generation of induced pluri...

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Bibliographic Details
Main Authors: Friedli, Marc, Turelli, Priscilla, Kapopoulou, Adamandia, Rauwel, Benjamin, Castro-Díaz, Nathaly, Rowe, Helen M., Ecco, Gabriela, Unzu, Carmen, Planet, Evarist, Lombardo, Angelo, Mangeat, Bastien, Wildhaber, Barbara E., Naldini, Luigi, Trono, Didier
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120079/
https://ncbi.nlm.nih.gov/pubmed/24879558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.172809.114
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