Poly (lactic acid)-poly (ethylene glycol) nanoparticles provide sustained delivery of a Chlamydia trachomatis recombinant MOMP peptide and potentiate systemic adaptive immune responses in mice

PLA-PEG [poly (lactic acid)-poly (ethylene glycol)], a biodegradable copolymer, is underexploited for vaccine delivery although it exhibits enhanced biocompatibility and slow release immune-potentiating properties. We document here successful encapsulation of M278, a Chlamydia trachomatis MOMP (majo...

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Hlavní autoři: Dixit, Saurabh, Singh, Shree R., Yilma, Abebayehu N., Agee, Ronald D., Taha, Murtada, Dennis, Vida A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119847/
https://ncbi.nlm.nih.gov/pubmed/24602605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.02.009
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