Local hyperthermia treatment of tumors induces CD8(+) T cell-mediated resistance against distal and secondary tumors

Combinatorial use of iron oxide nanoparticles (IONPs) and an alternating magnetic filed (AMF) can induce local hyperthermia in tumors in a controlled and uniform manner. Heating B16 primary tumors at 43°C for 30 minutes activated dendritic cells (DCs) and subsequently CD8(+) T cells in the draining...

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Main Authors: Toraya-Brown, Seiko, Sheen, Mee Rie, Zhang, Peisheng, Chen, Lei, Baird, Jason R., Demidenko, Eugene, Turk, Mary Jo, Hoopes, P. Jack, Conejo-Garcia, Jose R., Fiering, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119841/
https://ncbi.nlm.nih.gov/pubmed/24566274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.01.011
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