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Managing Cytokine Release Syndrome Associated With Novel T Cell-Engaging Therapies

Chimeric antigen receptor (CAR)-modified T cells and bispecific T cell–engaging antibodies have demonstrated dramatic clinical responses in recent clinical trials. The hallmark of these novel highly active immunotherapies is nonphysiologic T cell activation, which has correlated not only with greatl...

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Autori principali: Maude, Shannon L., Barrett, David, Teachey, David T., Grupp, Stephan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119809/
https://ncbi.nlm.nih.gov/pubmed/24667956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000035
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