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Effect of Duplicate Genes on Mouse Genetic Robustness: An Update

In contrast to S. cerevisiae and C. elegans, analyses based on the current knockout (KO) mouse phenotypes led to the conclusion that duplicate genes had almost no role in mouse genetic robustness. It has been suggested that the bias of mouse KO database toward ancient duplicates may possibly cause t...

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Main Authors: Su, Zhixi, Wang, Junqiang, Gu, Xun
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119742/
https://ncbi.nlm.nih.gov/pubmed/25110693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/758672
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