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The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay.

The hepatitis C virus RNA genome encodes a long polyprotein that is proteolytically processed into at least 10 products. The order of these cleavage products in the polyprotein is NH2-C-E1-E2-p7-NS2-NS3-NS4A-NS4B-NS5A-NS5B -COOH. A serine proteinase domain located in the N-terminal one-third of nons...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lin, C, Rice, C M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41197/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7622
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