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A systems biology approach to the effect of aging, immunosenescence and vaccine response

Aging can lead to immunosenescence, which dramatically impairs the hosts’ ability to develop protective immune responses to vaccine antigens. Reasons for this are not well understood. This topic’s importance is reflected in the increases in morbidity and mortality due to infectious diseases among el...

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Detalhes bibliográficos
Main Authors: Poland, Gregory A., Ovsyannikova, Inna G., Kennedy, Richard B., Lambert, Nathaniel D., Kirkland, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119552/
https://ncbi.nlm.nih.gov/pubmed/24820347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.04.005
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