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Recent BRCAPRO upgrades significantly improve calibration

The recent release of version 2.0-8 of the BayesMendel package contains an updated BRCAPRO risk prediction model, which includes revised modeling of Contralateral Breast Cancer (CBC) penetrance, provisions for pedigrees of mixed ethnicity and an adjustment for mastectomies among family members. We e...

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Detalhes bibliográficos
Main Authors: Mazzola, Emanuele, Chipman, Jonathan, Cheng, Su-Chun, Parmigiani, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119541/
https://ncbi.nlm.nih.gov/pubmed/24891549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-13-1364
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