Beta-lapachone inhibits pathological retinal neovascularization in oxygen-induced retinopathy via regulation of HIF-1α

Retinal neovascularization in retinopathy of prematurity (ROP) is the most common cause of blindness for children. Despite evidence that hypoxia inducible factor (HIF)-1α -VEGF axis is associated with the pathogenesis of ROP, the inhibitors of HIF-1α have not been established as a therapeutic target...

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Bibliographic Details
Main Authors: Park, Sung Wook, Kim, Jin Hyoung, Kim, Ko-Eun, Jeong, Moon Hee, Park, Hyunsung, Park, Bongju, Suh, Young-Ger, Park, Woo Jin, Kim, Jeong Hun
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119393/
https://ncbi.nlm.nih.gov/pubmed/24533641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12235
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