The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells

Protocadherin-15 (Pcdh15) is a component of the tip-links, the extracellular filaments that gate hair cell mechano-electrical transduction channels in the inner ear. There are three Pcdh15 splice isoforms (CD1, CD2 and CD3), which only differ by their cytoplasmic domains; they are thought to functio...

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Bibliografiske detaljer
Main Authors: Pepermans, Elise, Michel, Vincent, Goodyear, Richard, Bonnet, Crystel, Abdi, Samia, Dupont, Typhaine, Gherbi, Souad, Holder, Muriel, Makrelouf, Mohamed, Hardelin, Jean-Pierre, Marlin, Sandrine, Zenati, Akila, Richardson, Guy, Avan, Paul, Bahloul, Amel, Petit, Christine
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119359/
https://ncbi.nlm.nih.gov/pubmed/24940003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201403976
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