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The role of encapsulation by β-cyclodextrin in the interaction of raloxifene with macromolecular targets: a study by spectroscopy and molecular modeling

We report the binding of the drug raloxifene with Calf thymus DNA (ctDNA) and bovine serum albumin (BSA) in the presence and absence of β-cyclodextrin (β-CD) and explain the influence of β-cyclodextrin on the binding of the drug to macromolecules. UV-Vis absorption, fluorescence, proton nuclear magn...

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Detalhes bibliográficos
Main Authors: Sameena, Y., Sudha, N., Chandrasekaran, S., Enoch, Israel V. M. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119190/
https://ncbi.nlm.nih.gov/pubmed/25073419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-014-9355-y
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