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Preventing Olanzapine-Induced Weight Gain Using Betahistine: A Study in a Rat Model with Chronic Olanzapine Treatment

Olanzapine is the one of first line antipsychotic drug for schizophrenia and other serious mental illness. However, it is associated with troublesome metabolic side-effects, particularly body weight gain and obesity. The antagonistic affinity to histamine H(1) receptors (H(1)R) of antipsychotic drug...

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Detalhes bibliográficos
Main Authors: Lian, Jiamei, Huang, Xu-Feng, Pai, Nagesh, Deng, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118967/
https://ncbi.nlm.nih.gov/pubmed/25084453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104160
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