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Pharmacokinetic Evaluation of Oral Dantrolene in the Dog
The pharmacokinetics of dantrolene and its active metabolite, 5-hydroxydantrolene, after a single oral dose of either 5 mg/kg or 10 mg/kg of dantrolene were determined. The effects of exposure to dantrolene and 5-hydroxydantrolene on activated whole blood gene expression of the cytokines interleukin...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118838/ https://ncbi.nlm.nih.gov/pubmed/24219828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12089 |
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