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Employing whole genome mapping for optimal de novo assembly of bacterial genomes

BACKGROUND: De novo genome assembly can be challenging due to inherent properties of the reads, even when using current state-of-the-art assembly tools based on de Bruijn graphs. Often users are not bio-informaticians and, in a black box approach, utilise assembly parameters such as contig length an...

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Autores principales: Xavier, Basil Britto, Sabirova, Julia, Pieter, Moons, Hernalsteens, Jean-Pierre, de Greve, Henri, Goossens, Herman, Malhotra-Kumar, Surbhi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118782/
https://ncbi.nlm.nih.gov/pubmed/25077983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-484
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