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Cellular regulation of hemoglobin switching: evidence for inverse relationship between fetal hemoglobin synthesis and degree of maturity of human erythroid cells.

To investigate whether the level of maturity of human erythroid cells influences the expression of the fetal hemoglobin program, we studied the relative production of fetal (Hb F) and adult (Hb A) hemoglobins during the maturation of erythroid clones produced in vitro by adult or neonatal erythroid...

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Detalhes bibliográficos
Main Authors: Papayannopoulou, T, Kalmantis, T, Stamatoyannopoulos, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC411876/
https://ncbi.nlm.nih.gov/pubmed/293729
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