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KLF1: when less is more

In this issue of Blood, Liu et al gain an understanding of phenotypic variability in hemoglobinopathies.(1) They find that mutations in Krüppel-like factor-1 (KLF1) are significantly more prevalent in patients with β-thalassemia than previously recognized and correlate with a milder phenotype. This...

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Bibliografski detalji
Glavni autori: Manwani, Deepa, Bieker, James J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118480/
https://ncbi.nlm.nih.gov/pubmed/25082863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-576967
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