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Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models

Keratinocyte growth factor (KGF) is a paracrine-acting epithelial mitogen produced by cells of mesenchymal origin, that plays an important role in protecting and repairing epithelial tissues. Pre-clinical data initially demonstrated that a recombinant truncated KGF (palifermin) could reduce gastroin...

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Autori principali: Finch, Paul W, Mark Cross, Lawrence J, McAuley, Daniel F, Farrell, Catherine L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118166/
https://ncbi.nlm.nih.gov/pubmed/24151975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12091
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