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Mutational analysis of the simian virus 40 replicon: pseudorevertants of mutants with a defective replication origin.

The circular genome of simian virus 40 is a model mammalian replicon, containing a unique origin of replication (ori) and coding for a protein (SV40 T antigen) known to be involved in initiation of viral DNA replication and to bind in vitro to the origin region. Mutations within the ori sequence lea...

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Detalles Bibliográficos
Main Authors: Shortle, D R, Margolskee, R F, Nathans, D
Formato: Artigo
Idioma:Inglês
Publicado: 1979
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC411816/
https://ncbi.nlm.nih.gov/pubmed/230499
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