Role of Activating Transcription Factor 3 (ATF3) in Endoplasmic Reticulum (ER) Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis through Up-regulation of Death Receptor 5 (DR5) by Zerumbone and Celecoxib

Death receptor 5 (DR5) is a death domain-containing transmembrane receptor that triggers cell death upon binding to its ligand, TNF-related apoptosis-inducing ligand (TRAIL), and a combination of TRAIL and agents that increase the expression of DR5 is expected to be a novel anticancer therapy. In th...

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Hlavní autoři: Edagawa, Makoto, Kawauchi, Junya, Hirata, Manabu, Goshima, Hiroto, Inoue, Makoto, Okamoto, Tatsuro, Murakami, Akira, Maehara, Yoshihiko, Kitajima, Shigetaka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118115/
https://ncbi.nlm.nih.gov/pubmed/24939851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558890
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