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c-Abl Activates Janus Kinase 2 in Normal Hematopoietic Cells

Jak2 is involved in cytokine growth factor-stimulated signal transduction, but the mechanism of its activation is largely unknown. Here, we investigated Jak2 activation in a normal hematopoietic cell line, 32D mouse myeloid cells. The bimolecular fluorescence complementation studies showed that c-Ab...

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Hlavní autoři: Tao, Wenjing, Leng, Xiaohong, Chakraborty, Sandip N., Ma, Helen, Arlinghaus, Ralph B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118109/
https://ncbi.nlm.nih.gov/pubmed/24923444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554501
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