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Astragalin inhibits airway eotaxin-1 induction and epithelial apoptosis through modulating oxidative stress-responsive MAPK signaling

BACKGROUND: Eotaxin proteins are a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Since inflammation is often associated with an increased generation of reactive oxygen species (ROS), oxidative stress is a mechanistically imperative...

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Detalhes bibliográficos
Main Authors: Cho, In-Hee, Gong, Ju-Hyun, Kang, Min-Kyung, Lee, Eun-Jung, Park, Jung Han Yoon, Park, Sang-Jae, Kang, Young-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118077/
https://ncbi.nlm.nih.gov/pubmed/25069610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-122
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