Hypertonicity activates nonselective cation channels in mouse cortical collecting duct cells.
We investigated the effect of cell shrinkage on whole-cell currents of M-1 mouse cortical collecting duct cells. Addition of 100 mM sucrose to an isotonic NaCl bath solution induced cell shrinkage and increased whole-cell currents within 5-10 min by approximately 12-fold. The effect was reversible u...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41180/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7545304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.18.8478 |
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