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Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus

BACKGROUND: The determination of structural haplotypes at copy number variable regions can indicate the mechanisms responsible for changes in copy number, as well as explain the relationship between gene copy number and expression. However, obtaining spatial information at regions displaying extensi...

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Autors principals: Black, Holly A, Khan, Fayeza F, Tyson, Jess, Armour, John AL
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117965/
https://ncbi.nlm.nih.gov/pubmed/25048054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-614
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