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Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses.

Only three isoforms of adenylyl cyclase (EC 4.6.1.1) mRNAs (AC1, -2, and -5) are expressed at high levels in rat brain. AC1 occurs predominantly in hippocampus and cerebellum, AC5 is restricted to the basal ganglia, whereas AC2 is more widely expressed, but at much lower levels. The distribution and...

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Bibliographic Details
Main Authors: Mons, N, Harry, A, Dubourg, P, Premont, R T, Iyengar, R, Cooper, D M
Format: Artigo
Language:Inglês
Published: 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC41179/
https://ncbi.nlm.nih.gov/pubmed/7667314
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