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Spatial Invasion Dynamics on Random and Unstructured Meshes: Implications for Heterogeneous Tumor Populations
In this work we discuss a spatial evolutionary model for a heterogeneous cancer cell population. We consider the gain-of-function mutations that not only change the fitness potential of the mutant phenotypes against normal background cells but may also increase the relative motility of the mutant ce...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117853/ https://ncbi.nlm.nih.gov/pubmed/24462897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.01.009 |
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