Two cationic porphyrin isomers showing different multimeric G-quadruplex recognition specificity against monomeric G-quadruplexes

Ligands that can interact specifically with telomeric multimeric G-quadruplexes could be developed as promising anticancer drugs with few side effects related to other G-quadruplex-forming regions. In this paper, a new cationic porphyrin derivative, m-TMPipEOPP, was synthesized and characterized. It...

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Bibliographic Details
Main Authors: Huang, Xiao-Xi, Zhu, Li-Na, Wu, Bin, Huo, Yan-Fang, Duan, Na-Na, Kong, De-Ming
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117758/
https://ncbi.nlm.nih.gov/pubmed/24939896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku526
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