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Identification of RNA binding motifs in the R2 retrotransposon-encoded reverse transcriptase

R2 non-LTR retrotransposons insert at a specific site in the 28S rRNA genes of many animal phyla. R2 elements encode a single polypeptide with reverse transcriptase, endonuclease and nucleic acid binding domains. Integration involves separate cleavage of the two DNA strands at the target site and ut...

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Detalles Bibliográficos
Main Authors: Jamburuthugoda, Varuni K., Eickbush, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117753/
https://ncbi.nlm.nih.gov/pubmed/24957604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku514
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