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UNC5B receptor deletion exacerbates DSS-induced colitis in mice by increasing epithelial cell apoptosis

The netrin-1 administration or overexpression is known to protect colon from acute colitis. However, the receptor that mediates netrin-1 protective activities in the colon during colitis remains unknown. We tested the hypothesis that UNC5B receptor is a critical mediator of protective function of ne...

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Bibliografiske detaljer
Main Authors: Ranganathan, Punithavathi, Jayakumar, Calpurnia, Li, Dean Y, Ramesh, Ganesan
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117732/
https://ncbi.nlm.nih.gov/pubmed/24720832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12280
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