Macrophage-Activating Lipopeptide-2 Requires Mal and PI3K for Efficient Induction of Heme Oxygenase-1

AIMS: This study is to investigate the mechanisms by which macrophage-activating lipopeptide-2 (MALP-2) induces heme oxygenase (HO)-1, a cytoprotective enzyme that catalyzes the degradation of heme, in human monocytes. METHODS: Human monocytic THP-1 cells were cultured for transient transfection wit...

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Bibliographic Details
Main Authors:	You, Xiaoxing, Liu, Liangzhuan, Zeng, Yanhua, Li, Ranhui, He, Jun, Ma, Xiaohua, Jiang, Chuanhao, Zhu, Cuiming, Chen, Liesong, Yu, Minjun, Ou, Guangli, Wu, Yimou
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2014
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4117634/ https://ncbi.nlm.nih.gov/pubmed/25077631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103433
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Macrophage-Activating Lipopeptide-2 Requires Mal and PI3K for Efficient Induction of Heme Oxygenase-1

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