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Evidence for a two-domain structure of the terminal membrane C5b-9 complex of human complement.

Lipid vesicles carrying the purified membrane C5b-9 complex [C5b-9(m)] of complement were analyzed immunochemically and in the electron microscope after treatment with a combination of trypsin and alpha-chymotrypsin. Under reducing conditions, the externally oriented annulus was removed. The remaini...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bhakdi, S, Tranum-Jensen, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1979
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411754/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/293689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5872
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